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The image below highlights the mechanisms of both GLP-1 and GIP, along with a callout to the newest treatment optiona triple incretin that also includes glucagonexpected to be approved in late 2025 to early 2026

It was FDA-approved as Geref Diagnostic for evaluating pituitary growth hormone secretory capacity (2)

ESI India Guidelines Diabetic retinopathy worsening Rapid improvement in blood sugar in T2D patients can temporarily worsen pre-existing diabetic retinopathy

A small human study examining the addition of phentermine to liraglutide found no meaningful additional weight loss compared to liraglutide alone

Final Thoughts Theres no one-size-fits-all solution for perimenopause